Don’t just live with chronic sinusitis symptoms. Treat them with XHANCE.

The only FDA-approved medicine for adults with chronic rhinosinusitis without nasal polyps.

Nasal spray device diagram showing components: nosepiece, flexible mouthpiece, indented grip, and bottle

Medical Device Components Diagram

Detailed diagram of a nasal spray device showing four main components: The nosepiece at the top for nasal insertion, a flexible mouthpiece that uses your own breath to help deliver medicine into nasal passages, an indented grip section for secure handling, and the main bottle container at the bottom.

Device Components:

  • Nosepiece: For nasal insertion
  • Flexible Mouthpiece: Uses your breath to assist medicine delivery
  • Indented Grip: For secure handling
  • Bottle: Contains the medication

Prescribed online. Delivered to your home.

Is XHANCE right for you?

Check your symptoms—if you have at least 2 of these symptoms for 12 weeks (or more), you might have chronic sinusitis.

Stuffy nose

When your nasal passages are blocked, making it hard to breathe through your nose.

Facial pain or pressure

A common symptom of sinusitis that may worsen when bending forward.

Runny nose/nasal drip

Can include a runny nose or a drip down the back of the throat.

Reduction of sense of smell

This can happen when the mucous membranes in your nose are inflamed or blocked.

In clinical trials, patients experienced significant reduction in symptoms

Symptoms

Reductions after 4 weeks

Reductions after 12 weeks

Facial Pain or Pressure
27%
(placebo -15%)
45%
(placebo -31%)
Congestion
30%
(placebo -12%)
43%
(placebo -24%)
Runny Nose/Post Nasal Drip
26%
(placebo -14%)
42%
(placebo -24%)

XHANCE is the only medication proven to reduce the risk of chronic sinusitis flare-ups*

Sinusitis flare-ups are worsening of sinus symptoms that can require additional treatment (such as a doctor visit, antibiotics, and/or oral steroids).

*Reduction of risk was measured at 24 weeks and established with high dose (372 mcg twice daily) only. In two clinical studies using twice-daily dosing, flare-ups occurred in 15.7% of placebo users (41/187), 9.9% of XHANCE 186 mcg users (20/184), and 7.8% of XHANCE 372 mcg users (15/183).

Your breath helps deliver medicine high and deep into your nasal passages where chronic sinusitis occurs.

Unlike with other nasal sprays, you blow into XHANCE, instead of sniffing.

Get started with XHANCE

This link will take you to beyondMD for a 5-minute questionnaire, to be reviewed by a medical provider. These are independent providers; they are not paid by Optinose. You may be responsible to pay for a medical consultation (similar to an in-person office visit).

How to see if XHANCE is right for you

Complete a medical questionnaire

The first step toward relief is to fill out a short questionnaire to see if your symptoms are consistent with chronic sinusitis and if you are eligible for this program.

A beyondMD clinician will review your responses

A clinician must diagnose you with chronic sinusitis and determine if XHANCE is right for you.

Our pharmacy partner will check for coverage eligibility for XHANCE in this program

XHANCE is covered by most private health insurance.

If prescribed, our pharmacy partner will review your insurance information and apply any discounts you may be eligible for.

Eligible patients pay as little as $0 for your prescription*

Get XHANCE in 3 simple steps

*These offers are not valid for use by cash-paying patients or patients enrolled in Medicare, Medicaid, and TRICARE or other federal or state programs. Copay support and other offers are subject to quantity limitations. Maximum benefits per fill apply. Patient cost share may impact benefit and eligibility. Optinose® reserves the right to rescind, revoke, or amend this offer without notice. Click here for additional terms and conditions.

Step 1

Complete a brief medical questionnaire

See if your symptoms are consistent with chronic sinusitis, and add your insurance & payment info.

What you’ll need:

Photo ID

Payment Card (for $29 consultation fee)

Insurance Information

Step 2

Virtual medical provider assessment

No onsite visit—a licensed medical provider will determine if XHANCE is right for you (virtual assessment cost: $29.00).

Step 3

Delivered to your home

If prescribed and covered by your insurance, our pharmacy partner will fill your prescription for XHANCE, and deliver it to your home.

You think you’ve tried everything, but have you tried XHANCE?

XHANCE is the only FDA-approved medicine for adults with chronic rhinosinusitis without nasal polyps.

Frequently asked questions about XHANCE

Meet some members of the beyondMD medical team

Licensed medical providers will evaluate your symptoms, and make appropriate treatment decisions. These medical providers are independently owned and operated, and are not affiliated with Optinose. Optinose is not responsible for the medical care furnished through these medical providers.

Hollie Hall

Hollie Hall

Nurse Practitioner

John Bernard

John Bernard

MD, Medical Director

Angela Shannon

Angela Shannon

MD

Meghan McInnis

Meghan McInnis

Nurse Practitioner

Get started with XHANCE

Complete a brief medical questionnaire—you’ll need your photo ID, insurance info & payment card.

Indications

Important Safety Information

Indications

Important Safety Information